Table 1.

Demographic and clinical data of the study population. Continuous variables are expressed as median (range).

Age (years)	62 (40–77)
Male gender (%)	28 (80)
Etiology, n (%)
− HBV*	8 (22.9)
− HCV**	16 (45.7)
− Alcohol	7 (20.0)
− NASH/cryptogenic	4 (11.4)
Laboratory tests
− AST (U/L)	47.5 (11–268)
− ALT (U/L)	37 (7–217)
− Total bilirubin (mg/dl)	0.7 (0.4–27.7)
− Albumin (g/L)	41 (22–49)
− AFP (ng/ml)	10.35 (2–250)
− CA 19-9 (U/L)	41.5 (1–4920)
Tumor characteristics
− Nodule size (mm)	25 (10–100)
− Within Milan Criteria (%)	21 (60)
− Macrovascular invasion/  extrahepatic spread (%)	7 (20)

*Three patients had an HBV/HCV co-infection; **two patients had a concurrent alcohol abuse.

HBV: hepatitis B virus; HCV: hepatitis C virus; NASH: non-alcoholic steatohepatitis; AST: aspartate aminotransferase; ALT: alanine aminotransferase; AFP: alfa-fetoprotein.