Table 3.

Autoantibodies detected in Dermatomyositis.

Types of autoantibodies	Clinical Features
Myositis-specific antibodies:
Anti-synthetase/Anti-Jo1 Anti-SRP (signal reduction protein) Anti-Mi-2 Anti-MJ Anti-p155	Interstitial lung disease, Raynaud’s phenomenon, arthritis, ‘Mechanic’s hands’, absence of muscle involvement Severe necrotizing myositis Acute-onset, good response to therapy Juvenile DM, calcinosis, ILD Cancer-associated DM
Myositis-associated antibodies:
Anti-Ro Anti-La Anti-RNP Anti-Sm Anti-Scl	Sjogren’s syndrome Sjogren’s syndrome/SLE Mixed connective tissue disease SLE Scleroderma