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CAF-EV induce invasion of OSCC cells. (a) CAF-EV from each of the five cell lines were individually able to induce significantly the invasion of the tumour cells (HSC-3, SAS, SCC-15) in the myogel-coated transwell when compared to NOF-EV and to the control without vesicles. (b) Representative images of the invaded HSC-3 cells. (c) Pooled CAF-EV were also able to induce a higher invasion rate of HSC-3 cells. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001.
