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. 2019 Feb 6;22:101118. doi: 10.1016/j.redox.2019.101118

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. S3 — Polymorphisms in NRF2 and CX3CR1 genes associated with neurodegenerative disorders. Scheme of human NRF2 and CX3CR1 genes (modified from (68) and (77) respectively). In this figure, it is depicted the risk of genetic variations in the promoter, exon and introns of the Nfe2l2 and Cx3cr1 genes (red dots denote haplotypes that confer increased susceptibility in Alzheimer’s disease (AD), Parkinson’s disease (PD) and Amyloid lateral sclerosis (ALS) whereas green dots show haplotypes that are protective in PD).