Table 2.
Reported cases of primary allograft dysfunction due to myeloma cast nephropathy
| Case report | Age/gender | Etiology of ESRD | Time of diagnosis | Light chain | Treatment | Outcome |
|---|---|---|---|---|---|---|
| Geiger et al.[2] | 55 years/female | Unknown | POD 81 | Lambda | Melphalan + prednisone | Graft nephrectomy on POD 83 |
| Foster et al.[3] | 63 years/male | Diabetic nephropathy | POD 35 | Kappa | Thalidomide + dexamethasone + melphalan + prednisone | HD-dependent at POD 120 |
| Perkowska-Ptasinska et al.[4] | 51 years/male | Unknown | POD 21 | Lambda | Not available | Graft nephrectomy on POD 51 |
| Goel et al.[5] | 72 years/female | Unknown | POD 26 | Lambda | Plasmapheresis + bortezomib + dexamethasone | Recovery of graft function by POD 90 |
| Lingaraj et al.[1] | 45 years/male | Unknown | POD 3 | Lambda | Plasmapheresis + bortezomib + dexamethasone | Dialysis dependent and succumbed to sepsis on POD 37 |
| Index case | 63 years/male | Diabetic nephropathy | POD 14 | Lambda | Plasmapheresis + bortezomib + prednisolone | Dialysis dependent and had sudden cardiac death on POD 22 |
POD: Postoperative day, HD: Hemodialysis, ESRD: End stage renal disease