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. 2019 May;14(5):903–912. doi: 10.4103/1673-5374.249239

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Copyright: © Neural Regeneration Research

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Regenerative tissue in the rat sciatic nerve defect bridged with the aligned fiber nerve guide conduit.

(A) Analysis of regenerative matrix 49 days after implantation. (B) Tissue at 3 mm within the matrix in sections stained with cleaved caspase-3 antibody (green, Alexa Fluor 488, apoptotic cells). (C) NF200 antibody (green, Alexa Fluor 488, axons). Scale bars: 10 μm in B, 20 μm in C. (D, E) Comparison of the feet in rats implanted with aligned (D) and random (E) nanofiber nerve guide conduits. NF200: neurofilament 200; DAPI: 4′,6-diamidino-2-phenylindole.