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. 2019 Feb 14;12:33. doi: 10.1186/s12920-019-0478-7

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Schematic representation of the data anlysis work flow. The number of variants from each sample is tabulated. The filtered-out variants are highlighted in red, whereas the kept variants followed either path 1 or 2 (green)