Table 3.

Recommendations from CDC and other public health agencies for sexual health-related vaccinations and HIV pre- and post-exposure prophylaxis in men who have sex with men.^{3, 64}

Vaccination	Indications	Comment
HPV vaccination63	Through age 26, regardless of prior or current HPV infection status	3 doses of 4-valent or 9-valent vaccine; 2 doses if age 11–12
Hepatitis A virus vaccination3	No known prior or current infection, or prior vaccination	2–3 dose series depending on vaccine
Hepatitis B virus vaccination3	No known prior or current infection, or prior vaccination	3-dose series
Meningococcal vaccination33, 64	HIV-positive persons above age 2, including HIV-positive MSM	2-dose series of conjugated vaccine for serotypes A/C/W/Y
HIV Prophylaxis	Indications	Comment
Pre-Exposure Prophylaxis67	Adult man with: No HIV infection Any male sex partners in past 6 months Non in a monogamous relationship with a recently tested, HIV-negative man AND at least one of the following: Any anal sex without condoms (receptive or insertive) in past 6 months Any STD diagnosed or reported in past 6 months Is in an ongoing sexual relationship with an HIV-positive partner	Discuss and refer to PrEP providers to consider PrEP initiation, in addition to safer sex counseling to decrease risk of HIV acquisitiona
Non-Occupational Post-Exposure Prophylaxis72	Exposure with substantial risk for HIV acquisition within 72 hours from a source known to be HIV-positive; for other exposures with risk, consider on a case-by-case basis	Refer immediately for evaluation and treatment; must initiate nPEP within 72 hours of exposure

HIV, human immunodeficiency virus; HPV, human papillomavirus; PrEP, pre-exposure prophylaxis; nPEP, non-occupational post-exposure prophylaxis

^aA national directory of PrEP providers is at www.preplocator.org.⁷¹