Serum estradiol (A) and testosterone (B) concentrations are shown for F2 rats. (A) Serum estradiol in female and male rats. Maternal-lineage females were euthanized as adults on proestrus, whereas paternal females were euthanized on day 18 of pregnancy, indicated as E18. All male rats were euthanized between 4–4.5 mo of age. (B) Serum testosterone in the same adult male rats. Note: A1221, Aroclor 1,221; MAT, maternal; PAT, paternal; VEH, vehicle; VIN, vinclozolin. *; #, as determined using ANOVA followed by Tukey’s HSD posthoc analysis. Data shown are .