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. 2016 Apr;33(Suppl 3):19S–23S.

Table 3.

Screening Results

HBsAg Total anti-HBc IgM anti-HBc Anti-HBs Interpretation
Negative Negative Negative Negative Never infected and no evidence of infection
Positive Positive Negative Negative Chronic infection
Positive Positive Positive Negative Acute infection
Negative Positive Negative Positive Recovered from past infection and immune
Negative Negative Negative Positive Immune (Immunization or natural)

Abbreviations: anti-HBc, hepatitis B core antibody; anti-HBs, hepatitis B surface antibody; IgM anti-HBc, hepatitis B core IgM antibody.

Adapted from: Weinbaum CM, Williams I, Mast EE, et al; Centers for Disease Control and Prevention. Recommendations for identification and public health management of persons with chronic hepatitis B virus infection. MMWR Recomm Rep. 2008;57(RR-8):4.