Table 3.

Associations between a 50% reduction in residence proximity to major roadways at birth and methylation of CpG sites (cord blood) in gene regions with Gaussian kernel bandwidth of 1,000 nucleotide and a p-value cutoff of ${10}^{-08}$ ($\mathrm{N}=482$).

CHR	Gene	CpG	Gene group	CHR location	% change
3	LAMB2	cg01919208	1st exon	49170496	0.47%
3	LAMB2	cg02954987	TSS200	49170599	1.04%
3	LAMB2	cg05654765	TSS200	49170727	0.81%
3	LAMB2	cg14099457	TSS200	49170794	0.90%
3	LAMB2	cg03732535	TSS1500	49171051	0.20%
3	LAMB2	cg01638175	TSS1500	49171179	$-0.004\%$
3	LAMB2	cg05323436	TSS1500	49171185	$-0.004\%$
3	LAMB2	cg02497019	TSS1500	49171343	$-0.002\%$
2	C2orf65	cg20945085	TSS200	74875227	0.21%
2	C2orf65	cg02109484	TSS200	74875253	0.36%
2	C2orf65	cg17019053	TSS200	74875263	0.36%
2	C2orf65	cg00273449	TSS200	74875268	0.20%
2	C2orf65	cg17105755	TSS200	74875317	0.44%
2	C2orf65	cg02611848	TSS1500	74875387	0.35%
6	PPP1R2P1	cg02269978	Body	32847585	0.49%
6	PPP1R2P1	cg24639679	Body	32847590	0.65%
6	PPP1R2P1	cg19628603	Body	32847596	0.53%
6	PPP1R2P1	cg00797104	Body	32847605	0.42%
6	PPP1R2P1	cg17352045	Body	32847702	0.55%
6	PPP1R2P1	cg00892368	Body	32847704	0.58%

Note: Model adjusted for maternal [age at enrollment (continuous), pre-pregnancy BMI (continuous), race (white/black/others), smoking status (smoking during pregnancy/former/never), education level (college or graduate/not college or graduate)], neighborhood [median household income (continuous)], children [child’s sex (female/male), gestational age (continuous), season (DOB)], and estimated cell proportions (percentage of monocyte, percentage of CD8T cell, percentage of CD4T cell, percentage of NK cell, percentage of B cell, percentage of nucleated red blood cell). $\text{CHR},\text{chromosome}$.