Table 3:
Cox Proportional Hazard Model of 5-year overall survival, propensity- matched patients
| Covariate | Hazard Ratio | P Value |
|---|---|---|
| Age (decile) | 1.34 (1.17–1.57) | <0.001 |
| Gender | ||
| Male | -- | 0.122 |
| Female | 0.84 (0.67–1.05) | |
| Race | ||
| Caucasian | -- | 0.027 |
| African American | 0.44 (0.22–0.84) | |
| Other | 1.29 (0.78–2.13) | |
| Comorbidity | ||
| Cerebrovascular Disease | 1.26 (0.68–2.34) | 0.485 |
| COPD | 1.22 (0.97–1.53) | 0.090 |
| Congestive Heart Failure | 1.26 (0.89–1.80) | 0.206 |
| Coronary Artery Disease | 0.89 (0.68–1.17) | 0.355 |
| Diabetes | 1.60 (1.18–2.15) | 0.003 |
| Peripheral Vascular Disease | 1.00 (0.68–1.46) | 0.996 |
| Psychiatric History | 1.48 (1.01–2.17) | 0.073 |
| Substance Abuse | 0.92 (0.58–1.45) | 0.727 |
| Tumor size (mm) | 1.01 (0.99–1.02) | 0.544 |
| Positive margin | 1.04 (0.60–1.81) | 0.884 |
| Chemotherapy | 1.06 (0.73–1.53) | 0.782 |
| Radiation | 1.62 (0.96–2.65) | 0.037 |
| Pathologic Stage | ||
| Stage 1 | -- | 0.379 |
| Stage 2 | 1.44 (0.84–2.48) | |
| Stage 3 | 1.07 (0.47–2.41) | |
| Histology | ||
| Adenocarcinoma | -- | 0.175 |
| Squamous | 0.83 (0.63–1.09) | |
| Other | 0.72 (0.46–1.14) | |
| Histologic Grade | ||
| Well differentiated | -- | 0.025 |
| Moderately differentiated | 1.56 (1.13–2.16) | |
| Poorly Differentiated | 1.67 (1.19–2.34) | |
| Unknown | 1.26 (0.67–2.38) | |
| Resection type | ||
| Lobectomy | -- | 0.134 |
| Sublobar resection | 1.18 (0.95–1.47) | |