Skip to main content
. 2019 Feb 14;14(2):e0210646. doi: 10.1371/journal.pone.0210646

Table 3. Grade distribution (%) based on the last available audiogram according to different CTCAEv4.03, Muenster, SIOP, Brock and Chang classification systems.

Scale Grade 0,
n (%)
Grade 1a,
n (%)
Grade 1b,
n (%)
Grade 2a,
n (%)
Grade 2b,
n (%)
Grade 2c,
n (%)
Grade 3a,
n (%)
Grade 3b,
n (%)
Grade 3c,
n (%)
Grade 4,
n (%)
CTCAEv4.03 171 (32.8) 50 (9.6) 133 (25.5) 153 (29.3) 14 (2.7)
Muenster 129 (19.7) 186 (13.3) 52 (7.8) 89 (13.6) 97 (14.8) 55 (8.4) 69 (10.7) 33 (5) 45 (6.9)
SIOP 215 (32.9) 123 (18.8) 103 (15.8) 109 (16.7) 103 (15.8)
Brock 255 (39.1) 132 (20.2) 153 (23.5) 77 (11.8) 35 (5.4)
Chang 249 (38.2) 96 (14.7) 44 (6.7) 59 (9) 38 (5.8) 130 (19.9) 36 (5.5)

Abbreviations: CTCAE = U.S. National Cancer Institute Common Technology Criteria for Adverse Events, SIOP = International Society of Pediatric Oncology Boston