. 2019 Feb 14;14(2):e0210891. doi: 10.1371/journal.pone.0210891

Table 3. Most common adverse events^*.

Adverse event	Any grade		Grade 3 or 4
Adverse event	N	%	n	%
Alopecia	38	95	-	-
Anxiety	6	15	-	-
Bone pain	6	15	-	-
Constipation	9	23	-	-
Deranged transaminases	2	5	2	5
Diarrhoea	8	20	1	2
Dysgeusia	6	15	-	-
Dyspepsia	4	10	-	-
Fatigue	27	68	1	2
Febrile neutropenia	3	8	3	8
Gastro-oesophageal reflux	8	20	-	-
Headache	6	15	-	-
Insomnia	7	18	-	-
Nausea	25	63	-	-
Neutropenia	23	58	7	18
Sensory neuropathy	22	55	2	5
Pneumothorax	1	2	1	2

* Any grade reported for at least 10% of patients or grade ≥3 using CTCAE Version 4.0 reported for any patient. If a patient had more than one adverse event within a preferred term, the patient was counted once in the term.

Table 3. Most common adverse events*.

Table 3. Most common adverse events^*.