Table 3. Cut-off values for optimised sensitivity and specificity.
Cut-off value | AUC | Sensitivity | Specificity | Positive predictive value | Negative predictive value | Correctly classified instances | |
---|---|---|---|---|---|---|---|
Conventional quantification | |||||||
EDWT/LVEDViCQ (mm×m2/ml) | >0.14 | 0.998 | 99.5 | 98.0 | 95.5 | 99.3 | 99.4 |
LVMCQ/LVEDVCQ (g/ml) | >0.82 | 0.873 | 77.84 | 86.7 | 88.3 | 75.1 | 93.6 |
Threshold-based quantification | |||||||
EDWT/LVEDViTQ (mm×m2/ml) | >0.17 | 0.999 | 99.0 | 99.3 | 99.5 | 98.7 | 99.4 |
LVMTQ/LVEDVTQ (g/ml) | >1.27 | 0.948 | 89.2 | 91.3 | 93.0 | 86.7 | 94.4 |
Abbreviations: EDWT/LVEDVi, maximal end-diastolic wall thickness to left ventricular end-diastolic volume index ratio; LVM/LVEDV, left ventricular mass to left ventricular end-diastolic volume ratio evaluated using conventional (CQ) and threshold based quantification (TQ).