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. 2019 Feb 15;68(6):140–143. doi: 10.15585/mmwr.mm6806a3

TABLE 2. Crude and adjusted* probabilities of refill by number of days initially supplied and acute pain condition.

Condition No. of days initially supplied (95% CI)
3 5 7 14 28
Joint pain
Crude
0.20 (0.18–0.23)
0.20 (0.18–0.22)
0.20 (0.18–0.22)
0.18 (0.16– 0.21)
0.12 (0.05–0.24)
Adjusted
0.20 (0.17–0.22)
0.20 (0.18–0.22)
0.20 (0.18–0.22)
0.18 (0.16–0.22)
0.12 (0.05–0.25)
Back pain without radiculopathy
Crude
0.17 (0.16–0.19)
0.17 (0.16–0.18)
0.16 (0.15–0.17)
0.15 (0.13–0.17)
0.12 (0.09–0.17)
Adjusted
0.16 (0.14–0.18)
0.16 (0.14–0.17)
0.15 (0.14–0.17)
0.14 (0.12–0.16)
0.11 (0.08–0.16)
Headache
Crude
0.14 (0.11–0.17)
0.13 (0.11–0.15)
0.12 (0.097–0.14)
0.10 (0.07–0.15)
0.12 (0.03–0.38)
Adjusted
0.13 (0.10–0.16)
0.12 (0.093–0.14)
0.11 (0.086–0.14)
0.09 (0.07–0.14)
0.10 (0.02–0.31)
Neck pain
Crude
0.22 (0.18–0.25)
0.21 (0.18–0.24)
0.20 (0.18–0.22)
0.17 (0.13–0.22)
0.13 (0.06–0.26)
Adjusted
0.25 (0.20–0.30)
0.23 (0.19–0.28)
0.22 (0.19–0.26)
0.19 (0.14–0.25)
0.13 (0.06–0.26)
Tendonitis/Bursitis
Crude
0.17 (0.12–0.22)
0.17 (0.13–0.21)
0.17 (0.14–0.21)
0.18 (0.12–0.26)
0.21 (0.07–0.48)
Adjusted
0.17 (0.12–0.23)
0.17 (0.13–0.22)
0.18 (0.14–0.22)
0.19 (0.12–0.27)
0.21 (0.07–0.49)
Muscular strains/Sprains
Crude
0.17 (0.13–0.20)
0.16 (0.13–0.19)
0.15 (0.12–0.18)
0.13 (0.07–0.21)
0.09 (0.02–0.31)
Adjusted
0.16 (0.13–0.20)
0.16 (0.13–0.19)
0.15 (0.12–0.18)
0.13 (0.07–0.22)
0.09 (0.02–0.32)
Back pain with radiculopathy
Crude
0.31 (0.24–0.39)
0.33 (0.27–0.40)
0.28 (0.21–0.35)
0.21 (0.12–0.34)

Adjusted
0.24 (0.16–0.35)
0.27 (0.20–0.36)
0.21 (0.14–0.30)
0.15 (0.07–0.29)

Nephrolithiasis
Crude
0.21 (0.16–0.26)
0.20 (0.16–0.25)
0.20 (0.15–0.25)
0.18 (0.08–0.35)
0.15 (0.02–0.61)
Adjusted
0.22 (0.15–0.31)
0.22 (0.15–0.29)
0.21 (0.14–0.30)
0.19 (0.08–0.39)
0.16 (0.02–0.65)
Musculoskeletal injury
Crude
0.26 (0.12–0.47)
0.49 (0.27–0.72)
0.37 (0.18–0.62)
0.41 (0.13–0.77)

Adjusted
0.21 (0.086–0.44)
0.55 (0.30–0.79)
0.41 (0.19–0.68)
0.48 (0.15–0.84)

Dental pain
Crude
0.27 (0.21–0.33)
0.23 (0.19–0.29)
0.20 (0.14–0.28)
0.12 (0.04–0.31)
0.04 (0.003–0.39)
Adjusted 0.27 (0.21–0.33) 0.23 (0.18–0.29) 0.20 (0.14–0.28) 0.12 (0.04–0.31) 0.04 (0.003–0.39)

Abbreviation: CI = confidence interval.

* Adjusted for age, sex, and Charlson comorbidity score. (https://www.ncbi.nlm.nih.gov/pubmed/3558716). Probabilities calculated for the “average patient.”

Estimate is not informative because of sparse data. Twenty-eight days’ supply estimates are outside the range of data for most conditions.