Table 1.
Characteristics | Total | Aware of infection | Unaware of infection | p-value | |||
---|---|---|---|---|---|---|---|
N | Percent/IQR[95%CI]a | n | Percent [95%CI]a | n | Percent [95%CI]a | ||
Total | 710 | 100 | 251 | 36.6 [27.9,46.2] | 459 | 63.4 [53.8,72.1] | |
Sex | .086 | ||||||
Male | 327 | 46.9 [43.3,50.5] | 125 | 40.3 [29.6,51.9] | 202 | 59.7 [48.1,70.4] | |
Female | 383 | 53.1 [49.5,56.7] | 126 | 33.3 [25.3,42.3] | 257 | 66.7 [57.7,74.7] | |
Age at diagnosis, years | .385 | ||||||
10–11 | 420 | 59.6 [54.9,64.2] | 142 | 35 [25.8,45.4] | 278 | 65 [54.6,74.2] | |
12–14 | 290 | 40.4 [35.8,45.1] | 109 | 38.9 [28.9,50.0] | 181 | 61.1 [50.0,71.1] | |
Median age at HIV diagnosis | 589 | 11 [10–12] | 230 | 11 [10–12] | 359 | 11 [10–12] | |
Median age at enrollment into HIV care | 710 | 11 [10–12] | 251 | 11 [10–12] | 459 | 11 [10–12] | |
WHO stage | .109 | ||||||
I or II | 163 | 39.7 [33.2,46.6] | 69 | 45.4 [32.0,59.5] | 94 | 54.6 [40.5,68.0] | |
III or IV | 232 | 60.3 [53.4,66.8] | 80 | 35.5 [25.2,47.4] | 152 | 64.5 [52.6,74.8] | |
TB at enrollment/follow-up | .874 | ||||||
Ever TB | 217 | 31.6 [26.9,36.7] | 73 | 37.1 [26.2,49.6] | 144 | 62.9 [50.4,73.8] | |
NoTB | 493 | 68.4 [63.3,73.1] | 178 | 36.3 [27.2,46.4] | 315 | 63.7 [53.6,72.8] | |
Orphan status | .661 | ||||||
Both parents alive | 164 | 30.9 [26.5,35.6] | 62 | 40.4 [28.8,53.2] | 102 | 59.6 [46.8,71.2] | |
Orphan | 364 | 69.1 [64.4,73.5] | 147 | 42.9 [32.3,54.2] | 217 | 57.1 [45.8,67.7] | |
Caregiver | .426 | ||||||
Parents | 319 | 45.3 [39.9,50.9] | 124 | 40.1 [29.1,52.3] | 195 | 59.9 [47.7,70.9] | |
Other relatives | 294 | 41.4 [36.6,46.5] | 99 | 34.6 [26.3,44.0] | 195 | 65.4 [56.0,73.7] | |
Parents’ HIV status at enrollment | .013 | ||||||
Both mother and father HIV-infected | 66 | 9.5 [7.2,12.5] | 25 | 39.1 [25.2,55.0] | 41 | 60.9 [45.0,74.8] | |
Only one parent HIV-infected | 201 | 27.7 [23.5,32.4] | 88 | 47.2 [36.0,58.8] | 113 | 52.8 [41.2,64.0] | |
Mother’s & father’s HIV status unknown | 443 | 62.7 [56.9,68.3] | 138 | 31.5 [23.1,41.3] | 305 | 68.5 [58.7,76.9] | |
Immune status | .450 | ||||||
No significant immunosuppression | 147 | 33.4 [29.0,38.1] | 57 | 38.8 [28.2,50.5] | 90 | 61.2 [49.5,71.8] | |
Moderate | 69 | 15.0 [10.9,20.3] | 30 | 47.6 [31.2,64.5] | 39 | 52.4 [35.5,68.8] | |
Severe | 240 | 51.6 [44.7,58.5] | 90 | 39.7 [30.1,50.2] | 150 | 60.3 [49.8,69.9] | |
Current schooling status | .385 | ||||||
In school | 694 | 98.1 [90.8,99.6] | 245 | 36.6 [27.8,46.3] | 449 | 63.4 [53.7,72.2] | |
Dropped out | 9 | 1.9 [.4,9.2] | 2 | 21.8 [9.8,41.7] | 7 | 78.2 [58.3,90.2] | |
Parent(s) enrollment into care | .004 | ||||||
None/unknown | 531 | 75.1 [69.2,80.3] | 186 | 31.5 [23.2,41.1] | 365 | 68.5 [58.9,76.8] | |
Mother/father or both | 179 | 24.9 [19.7,30.8] | 82 | 51.9 [39.3,64.2] | 94 | 48.1 [35.8,60.7] | |
History of OIb at enrolment | .026 | ||||||
Did not have OIs | 134 | 20.9 [14.8,28.5] | 14 | 10.7 [4.9,21.6] | 120 | 89.3 [78.4,95.1] | |
Had OIs | 576 | 79.1 [71.5,85.2] | 237 | 42.7 [33.6,52.4] | 339 | 57.3 [47.6,66.4] | |
Ever had an OI† during follow-up | < .001 | ||||||
No OIs | 137 | 19.3 [13.3,27.1] | 38 | 24.5 [14.4,38.5] | 99 | 75.5 [61.5,85.6] | |
Developed OIs | 573 | 80.7 [72.9,86.7] | 213 | 39.7 [31.1,49.0] | 360 | 60.3 [51.0,68.9] | |
Ever hospitalized during follow-up | .494 | ||||||
Hospitalized | 94 | 13.6 [10.5,17.5] | 31 | 34.7 [23.4,48.1] | 63 | 65.3 [51.9,76.6] | |
Not hospitalized | 561 | 86.4 [82.5,89.5] | 211 | 38.8 [29.5,49.1] | 350 | 61.2 [50.9,70.5] | |
Enrolled in support group | .001 | ||||||
Yes, enrolled | 133 | 49.0 [35.8,62.4] | 95 | 73.9 [61.2,83.6] | 38 | 26.1 [16.4,38.8] | |
No, not enrolled | 147 | 51.0 [37.6,64.2] | 54 | 37.8 [27.2,49.6] | 93 | 62.2 [50.4,72.8] | |
ART status | < .001 | ||||||
On ART | 545 | 78.0 [72.5,82.6] | 221 | 41.8 [32.0,52.2] | 324 | 58.2 [47.8,68.0] | |
Not on ART | 165 | 22.0 [17.4,27.5] | 30 | 18.1 [10.7,29.0] | 135 | 81.9 [71.0,89.3] | |
Transferred from another facility | .097 | ||||||
Not transferred | 587 | 82.3 [77.1,86.4] | 201 | 34.9 [26.5,44.3] | 386 | 65.1 [55.7,73.5] | |
Transfer-ins | 123 | 17.7[13.6,22.9] | 50 | 44.2[31.6,57.6] | 73 | 5.8[42.4,68.4] |
ART, antiretroviral therapy; CI, confidence interval; IQR, interquartile range; OI, opportunistic infection; TB, tuberculosis
Weighted percentages.
Opportunistic infections.