Table 4.

Associations Between Baseline Amygdalar Activity and Change in Adiposity Measurements Over 1 Year

Independent Variable		Dependent Variable (End Point)				Dependent Variable (End Point)
		Δ Weight (kg)		Δ VAT (cm3)		Δ SAT (cm3)		Δ VAT/SAT		Δ Total Fat (cm3)		Δ Lean Tissue Volume (cm3)
Predictor	Covariate	Standardizedβ (95% CI)	P Value	Standardized β (95% CI)	P Value	Standardized β (95% CI)	P Value	Standardized β (95% CI)	P Value	Standardized β (95% CI)	P Value	Standardized β (95% CI)	P Value
Amygdalar activity (continuous)	Univariate	−0.09	0.19	0.65	<0.001	0.38	0.05	0.15	0.43	0.50	0.009	−0.16	0.41
		(−0.22, 0.04)		(0.30, 1.00)		(0.01, 0.75)		(−0.23, 0.52)		(0.13, 0.86)		(−0.53, 0.22)
	Age and sex	−0.05	0.50	0.70	<0.001	0.37	0.06	0.20	0.27	0.50	0.01	−0.18	0.35
		(−0.18, 0.09)		(0.36, 1.05)		(−0.02, 0.75)		(−0.16, 0.55)		(0.13, 0.87)		(−0.56, 0.20)
	Baseline BMI	−0.08	0.28	0.67	<0.001	0.40	0.04	0.14	0.45	0.52	0.006	−0.13	0.47
		(−0.21, 0.06)		(0.31, 1.02)		(0.03, 0.77)		(−0.24, 0.52)		(0.16, 0.88)		(−0.49, 0.23)
	Baseline VAT	−0.06	0.41	0.65	0.001	0.36	0.06	0.16	0.41	0.48	0.01	−0.20	0.29
		(−0.19, 0.08)		(0.29, 1.00)		(−0.02, 0.74)		(−0.22, 0.54)		(0.11, 0.85)		(−0.56, 0.17)
	Baseline SAT	−0.08	0.25	0.67	<0.001	0.39	0.03	0.15	0.43	0.51	0.004	−0.17	0.37
		(−0.21, 0.06)		(0.33, 1.01)		(0.04, 0.75)		(−0.23, 0.53)		(0.17, 0.86)		(−0.55, 0.21)
	Baseline VAT/SAT	−0.07	0.33	0.67	<0.001	0.39	0.05	0.14	0.44	0.51	0.008	−0.19	0.32
		(−0.21, 0.07)		(0.31, 1.02)		(0.01, 0.77)		(−0.22, 0.49)		(0.13, 0.88)		(−0.57, 0.19)
	Baseline total fat	−0.07	0.29	0.65	<0.001	0.37	0.05	0.15	0.42	0.49	0.008	−0.18	0.35
		(−0.21, 0.06)		(0.31, 1.00)		(0.01, 0.74)		(−0.23, 0.53)		(0.13, 0.84)		(−0.55, 0.19)

Serial VAT and SAT measurements were available in 68 subjects. Bold P values are <0.05.