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. 2018 Oct 30;49(3):864–874. doi: 10.1002/jmri.26285

Table 5.

Distribution of T2‐Weighted Imaging, BI‐RADS DCE‐MRI and Qualitative and Quantitative DWI Variables for Benign and Malignant Tumors

Total Benign (n = 74) Malignant (n = 136) P‐value
Lesion laterality 0.0086
right 45 (21.7) 58 (27.5)
left 29 (13.5) 78 (37.2)
Lesion size <.0001
mean (SD) 21.4 (20.36) 30.6 (23.95)
median(min‐max) 15.0 (6‐100) 30.6 (2‐100)
Mass shape <0.0001
oval 17(9.4) 14(7.8)
round 40(22.2) 21(11.7)
irregular 8(4.4) 80(44.4)
Mass margin <0.0001
circumscribed 54(30.2) 8(4.5)
irregular 6(3.4) 57(31.8)
spiculated 4(2.2) 50(27.9)
Mass internal enhancement characteristics <0.0001
homogenous 29(16.1) 18(10.0)
heterogeneous 18(10.0) 84(46.7)
rim enhancement 0(0.0) 11(6.1)
dark internal septations 19(36.7) 1(0.6)
NME Distribution 0.0071
focal 6 (20.0) 5(16.7)
regional 3(10.0) 9(30.0)
segmental 0(0.0) 7(23.3)
Internal enhancement pattern 0.003
homogenous 6(20.7) 3(10.3)
heterogeneous 2(6.9) 16(55.2)
clumped NA 2(6.9)
clustered ring NA NA
DWI
ADC mean (SD) 1433.4 (374.17) 902.9 (237.36) <0.0001
ADC max (SD) 2133.4 (405.54) 2041.6(442.34) <0.0001
ADC min (SD) 681.6 (481.57) 282.5 (306.86) <0.0001
DWI_ADCmeanCAT <0.0001
<1.255 × 10‐3mm2/s 24(11.4) 127(60.8)
>1.255 × 10‐3mm2/s 50(23.9) 9(4.3)
Signal intensity b0 0.0427
isointense 34(16.3) 44(21.1)
hyperintense 40(19) 92(44.0)
DWI pattern b850 <0.0001
homogenous 53(25.2) 43(20.6)
heterogeneous 19(9.1) 66(31.6)
rim appearance 2(0.96) 27(12.9)

High risk lesions includes: atypical ductal hypoplasia, sclerosing adenosis with atypia, metaplasia with atypia, metaplasia with atypia, complex sclerosing lesion, columnar cell changes with atypia.

Fibrocystic changes include: ductal hyperplasia, columnar cell changes, focal fibrosis, sclerosing adenosis, apocrine metaplasia, fibrocystic changes.

ADC = apparent diffusion coefficient; DWI = diffusion‐weighted imaging; NME = nonmass enhancement.