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. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: Circ Res. 2019 Feb 15;124(4):526–538. doi: 10.1161/CIRCRESAHA.118.313845

Figure 4. Spherical aggregation increases CPC myocardial retention independent of Notch expression.

Figure 4.

(A) DiR fluorescence of 2D CPCs, 3D CPCs, and 3D CPCs transduced with Notch1-shRNA (3D+Notch-i) via whole animal in vivo imaging over 28 days post-injection. (B) Changes in DiR fluorescence were measured over time and are presented as % of day 0 values with 95% confidence intervals. N=7 2D, N=7 3D, N=5 3D+Notch-i. *p≤0.05 for overall difference by treatment group with two-way repeated measures ANOVA with Bonferroni post-hoc analysis.