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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Genet Epidemiol. 2018 Nov 19;43(2):150–165. doi: 10.1002/gepi.22171

Figure 3.

Figure 3

Empirical power vs. OR(GxE) with independence between G and E (plots A-C). Based on genome-wide simulations of 1 million SNPs with 1000 repetitions and one designated causal SNP in each repetition. A) OR(G) = 1.0 & OR(E) = 1.0; B) OR(G) = 1.2 & OR(E) = 1.2; C) Both OR(G) and OR(E) are induced by the interaction effect and are not held constant.