Table II.
Top loci ranked by BMA 2DF P-value for G × PM2.5 interaction on asthma susceptibility
| Marginal (MA) | Case-Control (CC) | Case-Only (CO) | DF2 | BMA 2DF | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chr | SNP | MAF | OR(G) | P-Value | OR(GxE) | P-Value | OR(GxE) | P-Value | P-Value | Posterior CC | Posterior CO | P-Value |
| 22 | rs62227671 | 0.25 | 0.92 | 2.68E-01 | 2.57 | 7.61E-10 | 1.83 | 4.06E-07 | 2.88E-08 | 0.993 | 0.007 | 5.81E-09 |
| 20 | rs6122625 | 0.11 | 0.92 | 3.77E-01 | 2.48 | 2.17E-06 | 1.91 | 3.05E-05 | 7.83E-06 | 0.024 | 0.976 | 5.97E-08 |
| 2 | rs57504074 | 0.13 | 0.97 | 7.61E-01 | 2.03 | 6.82E-05 | 1.81 | 2.40E-05 | 3.26E-04 | 0.031 | 0.969 | 2.84E-07 |
| 8 | rs11137048 | 0.08 | 1.16 | 1.82E-01 | 2.20 | 2.09E-04 | 1.92 | 7.71E-05 | 3.90E-04 | 0.026 | 0.974 | 2.99E-07 |
| 5 | rs6866110 | 0.08 | 1.5 | 3.54E-01 | 0.50 | 1.06E-03 | 0.59 | 1.50E-03 | 7.64E-06 | 0.028 | 0.972 | 3.24E-07 |