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. Author manuscript; available in PMC: 2019 Jul 7.
Published in final edited form as: Mucosal Immunol. 2019 Jan 7;12(2):545–554. doi: 10.1038/s41385-018-0115-3

Figure 6. CXCL1 and CXCL2 are critical for chemotaxis of the influenza-infected lung with aging.

Figure 6.

The lung lysate from young and aged, infected mice were obtained and employed in chemotaxis assays with neutrophils purified from the bone marrow of young mice. Inhibiting CXCL1 or CXCL2 reduced neutrophil chemotaxis of aged (a) and young (b) lung lysate (P < 0.05 vs. control in age group). n = 3–6. * P < 0.05 (Mann-Whitney test). Isotype control antibody did not significantly reduce neutrophil chemotaxis. Data representative of one of two independent experiments, which yielded similar results. Data are expressed as mean ± SEM.