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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: Am J Transplant. 2018 Sep 17;19(3):633–645. doi: 10.1111/ajt.15072

Figure 5.

Figure 5.

Microarray analysis indicates absence myeloid cell-expressed C5aR1 specifically reduces the expression of genes involved in cell migration and locomotion. Heatmap (A) and enrichment analysis (B) of downregulated genes in microarrays of RNA obtained from flow-sorted intragraft CD11b+Ly6CloLy6G- cells on day 6 after BALB/c hearts were transplanted into MR1-treated C5ar1fl/fl (n=3) and C5ar1fl/flxLysM-Cre (n=4) recipients of BALB/c hearts. The genes that comprise these pathways are depicted in red font in A.