Table 1.
Impact of oral administration of pure PO and an optimized SNEDDS F1 in comparison with standard gentamycin on circular excision wound model in rats at different days of treatment
| Formulations | Wound area of contraction ± SEM (%) | ||||||
|---|---|---|---|---|---|---|---|
| 0 Day | 4th Day | 8th Day | 12th Day | 16th Day | 20th Day | 24th Day | |
| Control | 0.00 ± 0.00 | 18.19 ± 2.40 | 39.49 ± 2.43 | 69.37 ± 1.85 | 85.15 ± 1.55 | 97.46 ± 0.56 | 99.49 ± 0.10 |
| Pure PO | 0.00 ± 0.00 | 19.60 ± 2.16 | 46.97 ± 2.43 | 72.54 ± 1.80 | 86.85 ± 1.30 | 98.65 ± 0.18 | 99.84 ± 0.09 |
| SNEDDS F1 | 0.00 ± 0.00 | 47.72 ± 1.44 | 64.77 ± 2.10 | 89.14 ± 0.70 | 92.67 ± 1.44 | 98.93 ± 0.15 | 100.00 ± 0.00 |
| Gentamycin | 0.00 ± 0.00 | 61.03 ± 0.73 | 78.58 ± 0.43 | 90.25 ± 0.67 | 95.46 ± 0.73 | 99.53 ± 0.14 | 100.00 ± 0.00 |