Table 4.

The median histopathologic scores of wound healing determined after oral administration of pure PO and an optimized SNEDDS F1 in comparison with and control and standard gentamycin using a modified 0–5 numerical scale; the scores were 0 for absence, 1 for occasional presence, 2 for light scattering, 3 for abundance, 4 for confluence of cells and 5 for fibres

Formulations	Epithelialisation	Inflammatory cell infiltration	Fibroblast proliferation	Neovascularization	Collagen deposition
Gentamycin	4.02 ± 0.29	1.89 ± 0.51	4.10 ± 0.38	3.10 ± 0.23	4.23 ± 0.61
SNEDDS F1	3.93 ± 0.21	1.60 ± 0.25	4.10 ± 0.50	2.83 ± 0.23	3.93 ± 0.31
Pure PO	2.20 ± 0.32	2.60 ± 0.32	2.53 ± 0.52	2.01 ± 0.35	2.50 ± 0.25
Control	0.83 ± 0.41	3.17 ± 0.22	1.00 ± 0.00	0.88 ± 0.35	1.01 ± 0.41