Table 2.
Axial scores after surgery and at time of test with different DBS frequencies.
| Post-surgery followup | Test day-clinical scores at DBS test frequencies | Test day | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| column ID | (A) | (B) | (C) | (D) | (E) | (F) | (G) | (H) | (I) | (J) | (K) | (L) |
| patient ID | Clinical score* | DBS original freq (Hz) | 40 Hz | 60 Hz | 80 Hz | 100 Hz | 120 Hz | 140 Hz | Mean optimal gait freq (Hz) | Clinical score (column C to H) at original freq [i.e., B]‡ | Time since surgery (y) | Rate of clinical score change at original freq [i.e., (J-A)/K] |
| OP01 | 1 | 130 | 10 | 8 | 4 | 6 | 4 | 140 | 5 | 10 | 0.44 | |
| OP02 | 2 | 130 | 5 | 6 | 3 | 5 | 3 | 3 | 140 | 3 | 5 | 0.25 |
| OP03 | 2 | 130 | 4 | 4 | 3 | 3 | 3 | 120 | 3 | 9 | 0.17 | |
| OP04 | 3 | 130 | 4 | 3 | 5 | 6 | 70 | 6 | 8 | 0.43 | ||
| OP05 | 2 | 130 | 2 | 3 | 2 | 2 | 3 | 2 | 100 | 2.5 | 4 | 0.17 |
| OP06 | 2 | 130 | 5 | 3 | 2 | 2 | 4 | 6 | 80 | 5 | 6 | 0.55 |
| OP07 | 1 | 160 | 3 | 3 | 2 | 2 | 1 | 2 | 100 | 2 | 13 | 0.17 |
| OP08 | 5 | 160 | 8 | 4 | 8 | 8 | 8 | 100 | 8 | 6 | 0.60 | |
| OP09 | 6 | 130 | 4 | 3 | 3 | 3 | 3 | 3 | 100 | 3 | 7 | −0.50 |
| OP10 | 1 | 130 | 2 | 3 | 3 | 2 | 100 | 2.5 | 8 | 0.21 | ||
| OP11 | 3 | 130 | 6 | 4 | 3 | 4 | 5 | 5 | 80 | 5 | 7 | 0.33 |
| OP12 | 4 | 130 | 3 | 3 | 4 | 2 | 4 | 120 | 3 | 4 | −0.33 | |
| OP13 | 1 | 130 | 3 | 2 | 2 | 2 | 2 | 120 | 2 | 7 | 0.17 | |
| OP14 | 3 | 130 | 5 | 1 | 2 | 1 | 2 | 1 | 80 | 1.5 | 5 | −0.38 |
| OP15 | 4 | 130 | 2 | 1 | 2 | 2 | 2 | 2 | 100 | 2 | 5 | −0.50 |
| OP16 | 0 | 130 | 2 | 3 | 5 | 3 | 5 | 3 | 80 | 4 | 10 | 0.44 |
| OP17 | 4 | 200 | 2 | 0 | 1 | 120 | 1 | 8 | −0.43 | |||
| OP18 | 1 | 130 | 8 | 7 | 9 | 8 | 80 | 8.5 | 10 | 0.83 | ||
| OP19 | 2 | 130 | 3 | 5 | 6 | 5 | 90 | 5.5 | 11 | 0.35 | ||
| OP20 | 2 | 185 | 2 | 2 | 5 | 2 | 2 | 2 | 120 | 2 | 9 | 0.00 |
| OP21 | 3 | 130 | 4 | 2 | 2 | 2 | 2 | 80 | 2 | 6 | −0.20 | |
| OP22 | 4 | 130 | 4 | 3 | 6 | 2 | 2 | 2 | 140 | 2 | 4 | −0.60 |
| OP23 | 3 | 130 | 5 | 3 | 2 | 2 | 4 | 3 | 100 | 3.5 | 4 | 0.17 |
| OP24 | 5 | 130 | 8 | 8 | 7 | 8 | 10 | 80 | 9 | 5 | 1.33 | |
Clinical scores measured off medication using items from UPDRS part III: Arise from chair, Posture, Gait, Pull test. Clinical scores collected at post-surgery follow-up are reported in column A, for the stimulation frequency chronically used at the time (column B). Clinical scores on test day at original frequency are reported in bold (column C-H, averaged in column J). Clinical scores on test day at optimal frequency are underlined (column C-H).
Recorded at 1 year after surgery except for OP03 (3 y), OP06 (0.5 y), OP07 (7 y), OP22 (0.67 y), OP24 (2 y). These differences were taken into account when calculating rate of axial score change.
If patient's original frequency was not tested at test day, the score was taken as either the average of scores at the frequencies above and below original frequency or the score at the nearest frequency if original frequency was higher than test-day frequencies.