Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 8;10:15. doi: 10.3389/fpsyt.2019.00015

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Deng, Yan, Zhu, Ma, Fan, Liu, Li and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Memantine decreased food intake. (A) Schematic representation of standard food intake test protocol by memantine. (B) 5 mg/kg memantine group showed similar Ctrl food intake with saline group (unpaired Student's t-test, P = 0.241). (C) 20 mg/kg memantine group significantly reduced the Ctrl food intake compared to saline group (unpaired Student's t-test, P = 0.0008). (D) Schematic representation of CTA behavioral protocol. (E) LiCl group and memantine group decreased the intake of sodium saccharin solution [group, F_{(3, 28)} = 4.707, P = 0.01, one way ANOVA], post-hoc analysis revealed LiCl, 5 and 20 mg/kg memantine group increased the aversion index to 72.88% (P = 0.011), 74.43% (P = 0.008), and 82.29% (P = 0.002) respectively, compared to 43.63% of saline group.