Table 2.

Inhibitory activity of the synthesized probes against the hERG potassium channel^a.

Compd	IC50 (nM)	$K_i^b$ (nM)
L1	102.50	57.58
L2	155.90	87.58
L3	0.32	0.18
L4	1.05	0.59
Astemizole	11.25	6.32

^asee supporting information. ^bthe inhibition constant (K_i) was calculated from each IC₅₀ value using the Cheng–Prusoff equation.