Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Feb 8;13:4. doi: 10.3389/fncel.2019.00004

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Montroull, Danelon, Cragnolini and Mascó.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

TrkB-Fc increases neuronal death after SE in vivo. (A) Micrographs of hippocampal CA1 stained with Nissl (left panels) or with Fluoro-Jade B (FJB; right panels) show representative brain sections of animals with each treatment. Insets show, at higher magnification, morphological alterations evidenced by Nissl staining. Either TrkB-Fc or vehicle were infused in the hippocampi of one hemisphere (ipsilateral) of control (saline) and SE animals. (B) Quantification of the ipsilateral/contralateral FJB positive neurons in CA1 area. (C) Micrographs of hippocampal hilus stained with FJB show representative brain sections of animals with each treatment. (D) Quantification of the ipsilateral/contralateral FJB positive neurons in hippocampal hilus. Results are expressed as a mean ± SEM of three animals per treatment. Asterisk indicates p < 0.05 compared to vehicle by nested ANOVA. Scale bar = 200 μm.