Table 1.

Temperature-sensitive mutants identified in the screen and the derived mutants.

Original mutants		Derived mutants
Name	Mutations	Name	Mutations
# 1	L202V,F237L,Y261S,V274E,Y299S
# 2	L202M,R218G,S298R,L362S,S386F
# 3	P175H,D278V,R339S	D278V/R339S	D278V,R339S
# 4	N283Y,D293N,E439G	N283Y/D293N	N283Y,D293N
# 5	A221D,M242K, D337V	A221D/D337V	A221D,D337V
# 6	L194H,E415D	L194H	L194H