Table 1.
Factor effects from screening the Cecropia species leaves extraction process by FFD.
| Factor | Effects | ||
|---|---|---|---|
| TF | CA | FL | |
| A | −92.88* | −19.99* | 1.12* |
| B | 38.54 | 9.66 | −0.05 |
| C | 76.98 | 24.70* | 0.94* |
| D | 149.19* | 31.99* | 1.55* |
| E | 39.50 | 18.37* | 0.40 |
| F | 12.65 | 0.58 | 0.85 |
| G | −73.20 | −13.01* | −0.03 |
| A × B | −22.59 | −6.84 | −0.08 |
| A × C | −14.37 | 1.38 | −0.20 |
| A × D | 50.12 | 4.40 | −0.44 |
| A × E | −8.85 | −3.20 | −0.31 |
| A × F | −24.34 | −5.63 | −0.08 |
| A × G | −47.06 | −3.64 | −0.02 |
| B × D | −27.05 | 1.27 | −0.45 |
| Ecritical | 84.54 | 10.97 | 0.47 |
Factors: (A) methanol fraction (%, v/v), (B) extraction time (min), (C) number of methanol extractions, (D) temperature (°C), (E) mass:solvent ratio (w/v), (F) number of acetone extractions, (G) particle size of the plant material (µm). Responses: sum of peak areas of total flavonoids (TF), chlorogenic acid (CA) and flavonolignans (FL). The responses are represented as mean; SD are not given. *Significant effects.