Table 2.

Results of GWAS enrichment analysis in modules correlated with alcohol dependence and alcohol consumption

	RNA-Seq data (N = 138)						GWAS data
	Module trait correlation						GWAS P 0.05, eQTL P < 5 × 10−8
ID	AD	P	Audit	P	AC	P	PGC-AD	UKBB-AC	TAG-CPD
Thistle2	−0.28	9.00E-04	−0.25	3.00E-03	−0.22	9.00E-03	1.50E-02a	1.30E-02a	5.52E-01a
Brown4	0.18	4.00E-02	0.14	1.00E-01	0.12	1.00E-01	4.20E-03b	2.28E-01b	4.81E-03b

AD alcohol dependence, Audit audit scores, AC alcohol consumption

^a Permuted P value for the left-tail Fisher’s exact test (under-enriched)

^b Permuted P value to test right-tail Fisher’s exact test (over-enriched)