Table 1.
Patient characteristics
| HF (LVAD/explant) (n = 40) | HTX (n = 29) | p Value | |
|---|---|---|---|
| Anthropometry | |||
| Sex [% male] | 85 | 79 | 0.75 |
| Age [years] | 57 ± 11 | 57 ± 12 | 0.93 |
| BMI [kg/m2] | 26.6 ± 4.8 | 26.2 ± 4.1 | 0.69 |
| Comorbidities | |||
| T2DM [%] | 28 | 38 | 0.44 |
| Terminal CKD [%] | 13 | 10 | >0.99 |
| Arterial hypertension [%] | 45 | 38 | 0.63 |
| COPD [%] | 20 | 10 | 0.34 |
| Cardiac characteristics | |||
| EF [%] | 26.1 ± 16.6 | 66.3 ± 6.9 | <0.0001 |
| Cardiac index [l/min/m²] | 1.7 ± 0.3 | 2.9 ± 0.6 | <0.0001 |
| Time post-HTX [months] | – | 15.8 ± 7.1 | – |
| ICM [%] | 55 | 38 | 0.22 |
| DCM [%] | 45 | 66 | 0.14 |
| Lab values | |||
| Creatinine [mg/dl] | 1.5 ± 0.7 | 1.3 ± 0.5 | 0.37 |
| CRP [mg/dl] | 4.4 ± 6.0 | 1.3 ± 3.6 | 0.0006 |
| LDL [mg/dl] | 90 ± 38 | 106 ± 28 | 0.10 |
| HbA1c [%] | 5.7 ± 0.6 | 6.3 ± 1.0 | 0.02 |
| HbA1c [mmol/mol] | 38.3 ± 7.0 | 45.1 ± 11.2 | 0.02 |
BMI body mass index, CKD chronic kidney disease, COPD chronic obstructive pulmonary disease, CRP C-reactive protein, DCM dilated cardiomyopathy, EF left ventricular ejection fraction, HF heart failure, HTX heart transplantation, ICM ischemic cardiomyopathy, LDL low-density lipoprotein, LVAD left ventricular assist device, T2DM diabetes mellitus type 2.
Means ± SD; p-values calculated with the unpaired t-test/Mann–Whitney test