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. 2019 Feb 14;9:2018. doi: 10.1038/s41598-018-38336-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Rosiglitazone reduced LPS mediated invasion in trophoblast cell line HTR- 8/SVneo. (A) Graph shows the average number of cells counted in the lower chamber in the matrigel invasion assay with HTR-8/SVneo cells. Treatment with LPS significantly increased number of cells in the lower chamber which reduced when treated with Rosiglitazone. (B) Representative images show cells in the lower chamber in wells with respectively labelled treatments. n = 6, ‘*’ indicates significance at p < 0.05 when compared to the PBS control group, ^‘#’ indicates significance at p < 0.05 when compared to the LPS treated group. Scale bar: 50 µm.