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. 2018 Aug 25;597(4):1073–1085. doi: 10.1113/JP275810

Figure 2. Haemodynamic and ventricular characterization of pulmonary hypertension.

Figure 2

A–E, serial ECG of differences between WT (black lines) vs. BERK‐SS mice (red lines). Insets all WT groups combined vs. all BERK‐SS groups combined. †P < 0.0001 (n = 6–8). F, RVSP. * P < 0.01 BERK‐SS 8000 feet (solid bars) vs. WT mice (open bars) for all elevations (n = 6–8). †P < 0.01, BERK‐SS 8000 feet vs. Berk‐SS (sea level) (n = 6–8). G, RV weight. * P < 0.04 for BERK‐SS (solid bars) vs. WT mice (open bars) at each corresponding altitude. †P < 0.01 (n = 6–8) BERK‐SS 8000 feet vs. Berk‐SS (sea level). H, left ventricular weight. * P < 0.03 (n = 6–8) for BERK‐SS (solid bars) vs. WT mice (open bars) at each corresponding altitude. I, Fulton index. * P = 0.01 (n = 6–8) BERK‐SS vs. WT mice housed at 8000 feet. †P < 0.01 (n = 6–8) BERK‐SS mice housed at 8000 feet vs. BERK‐SS (solid bars) and WT mice (open bars) housed at sea level. J, CS. * P = 0.001 (n = 5) BERK‐SS (solid bars) vs. WT (open bars) housed at 5280 feet. ** P = 0.021 (n = 5) BERK SS (solid bars) vs. WT (open bars) housed at 8000 feet. †P ≤ 0.037 (n = 5) BERK‐SS housed at sea level vs. BERK‐SS housed at 5280 feet and 8000 feet. [Color figure can be viewed at wileyonlinelibrary.com]