Table 2.
Change in Body Composition among African Ancestry Men Who Did and Did Not Develop a Mobility Limitation Over 6 y
| Mobility Intact, n = 430 (85.1%) | Incident Mobility Limitations,* n = 75 (14.9%) | ||||
|---|---|---|---|---|---|
| pQCT | Absolute Δ | Percent Δ | Absolute Δ | Percent Δ | p Value |
| Total fat, cm2 | 1.4 (4.5)† | 9.4 (29.5) | 3.8 (7.7) | 21.8 (42.9) | .02 |
| subQ fat, cm2 | 0.9 (3.8) | 13.2 (54.8) | 2.6 (8.8) | 40.9 (163.1) | .12 |
| IMAT, cm2 | 0.5 (2.7) | 62.4 (161.9) | 1.6 (4.3) | 101.9 (250.5) | .04 |
| Muscle CSA, cm2 | −1.5 (7.1) | −2.1 (10.0) | −5.9 (7.9) | −8.4 (11.4) | <.01 |
| Muscle density, HU | −2.6 (3.3) | −3.5 (4.6) | −4.3 (4.6) | −6.3 (6.9) | .01 |
| Weight, kg | −0.9 (5.9) | −0.8 (7.3) | −1.6 (7.3) | −2.4 (10.5) | .21 |
| DXA | |||||
| Total fat, kg | 2.4 (3.8) | 16.5 (26.3) | 3.7 (4.8) | 20.3 (30.2) | .03 |
| Trunk fat, kg | 1.4 (2.1) | 19.7 (31.1) | 1.9 (2.6) | 21.2 (33.7) | .09 |
| Total lean, kg | −3.7 (2.8) | −6.3 (4.6) | −5.1 (3.4) | −8.4 (5.6) | <.01 |
| Appendicular lean, kg | −1.8 (1.5) | −6.5 (5.3) | −2.5 (1.9) | −8.9 (6.8) | .01 |
Note: CSA = Cross-sectional area; DXA = Dual x-ray absorptiometry; IMAT = Intermuscular adipose tissue; pQCT = Peripheral computed tomography.
*Incident mobility limitations: any difficulty walking two to three blocks or climbing up 10 steps due to a health/physical problem.
†Data are expressed as mean (SD).