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. 2018 Jul 18;68(5):738–747. doi: 10.1093/cid/ciy563

Table 2.

Pathogen Identification for the 175 Patients of 216 With Laboratory Diagnoses, Recruited to a Murine Typhus Clinical Trial

Pathogen Patients, No.
Total Culture PCR Serology
Rickettsia typhi 158a,b NA 53a 155b
Orientia tsutsugamushi 7 NA 6 4
Salmonella enterica Typhic 5 5 NA NA
Leptospira spp. 4 NA 4a NA
Escherichia coli c 1 1 NA NA
Salmonella enterica Paratyphi Ac 1 1 NA NA

Abbreviations: NA, not applicable; PCR, polymerase chain reaction.

aOne patient was PCR positive for both R. typhi and Leptospira sp.

bA total of 160 patients had serologic evidence of R. typhi infection, but 5 had PCR/culture evidence of another pathogen (E. coli, Salmonella Typhi, and Leptospira sp. in 1 each and O. tsutsugamushi in 2). They may have had concurrent dual infections, but we have opted to be conservative and not included these 5 patients, giving a denominator of 155 patients.

cBlood culture and bacterial identification as described by Phetsouvanh et al [21].