Table 3.

Significant SNPs identified in single marker-based association analyses stratified by clinical severity of chronic periodontitis.

Gene	SNP	Chr	A1	Moderate (N = 2,457)			Severe (N = 2,787)
				χ2	P	OR	χ2	P	OR
SIGLEC5	rs2278831	19	G	32.99	9.27 × 10−9	1.74	25.07	5.52 × 10−7	0.61
SIGLEC5	rs556418978	19	T	23.18	1.47 × 10−6	1.79	7.28	0.0070	0.71
SIGLEC5	rs4801882	19	G	20.88	4.89 × 10−6	1.44	13.11	0.0003	0.80
SIGLEC5	rs73050865	19	G	15.66	7.57 × 10−5	1.75	3.62	0.0573	0.75
SIGLEC5	*rs4284742	19	A	14.71	0.0001	1.41	73.58	9.68 × 10−18	0.46
NIN	*rs12883458	14	C	10.61	0.0011	1.49	13.35	0.0003	1.43
SIGLEC5	rs4802831	19	C	4.84	0.0278	1.37	7.31	0.0068	0.68

Chr: chromosome; A1: tested allele.

*Significant SNPs identified in single marker-based association analyses.