. 2019 Jan 1;9(2):355–368. doi: 10.7150/thno.29137

Table 2.

Serum biomarkers in mice after treatment with different PTX formulations (n = 3).

Groups	ALT (U/L)	ALP (U/L)	BUN (mM)	CRE (μM)
PBS	42.25 ± 4.03	114.1 ± 12.0	6.78 ± 0.35	34.5 ± 2.12
PTX-Lip (50 mg/m²)	40.05 ± 4.17	106.3 ± 16.3	6.80 ± 0.67	37.0 ± 2.83
PTX-Lip (100 mg/m²)	114.2 ± 4.88**	140.8 ± 9.69*	6.46 ± 0.71	32.3 ± 3.18
Free PTX (100 mg/m²)	369.8 ± 3.11***	191.5 ± 16.3*	6.66 ± 0.96	34.5 ± 2.12

ALT: glutamic-pyruvic transaminase; ALP: alkaline phosphatase; BUN: urea nitrogen; CRE: creatinine.

*P < 0.05, **P < 0.01, and ***P < 0.001 vs. PBS group.