Table 2. Clinical characteristics of the eyes in the two groups after 1, 3, 6 and 12mo compared with the baseline measurements.
| Groups | 1mo | 3mo | 6mo | 12mo | bP |
| ΔUCVA | |||||
| I-CXL 5min | -0.07±0.32 | -0.11±0.29 | -0.05±0.32 | -0.07±0.24 | 0.302 |
| I-CXL 10min | -0.19±0.26 | -0.16±0.28 | -0.15±0.32 | -0.13±0.27 | 0.025 |
| aP | 0.230 | 0.649 | 0.370 | 0.491 | |
| ΔCDVA | |||||
| I-CXL 5min | -0.01±0.15 | -0.03±0.18 | -0.01±0.18 | -0.03±0.24 | 0.674 |
| I-CXL 10min | -0.11±0.20 | -0.12±0.23 | -0.14±0.22 | -0.11±0.23 | 0.021 |
| aP | 0.101 | 0.229 | 0.053 | 0.264 | |
| ΔSphere | |||||
| I-CXL 5min | 0.55±1.58 | 1.15±2.37 | 0.58±3.51 | 0.77±2.46 | 0.004 |
| I-CXL 10min | 0.32±1.52 | 0.41±2.43 | 0.39±1.74 | 0.22±2.14 | 0.604 |
| aP | 0.644 | 0.351 | 0.818 | 0.462 | |
| ΔCylinder | |||||
| I-CXL 5min | 0.13±2.26 | 0.48±2.88 | 1.15±2.39 | 0.58±2.35 | 0.352 |
| I-CXL 10min | -0.04±1.42 | -0.32±1.6 | -0.16±1.52 | -0.47±1.82 | 0.772 |
| aP | 0.766 | 0.355 | 0.037 | 0.182 | |
| ΔSE | |||||
| I-CXL 5min | 0.62±1.46 | 1.39±2.63 | 1.16±3.87 | 1.06±2.76 | 0.160 |
| I-CXL 10min | 0.30±1.26 | 0.43±2.07 | 0.31±1.33 | 0.17±1.86 | 0.639 |
| aP | 0.467 | 0.204 | 0.313 | 0.227 | |
| ΔKsteep | |||||
| I-CXL 5min | 1.17±1.65 | 0.82±1.56 | 1.12±1.71 | 0.93±1.89 | 0.078 |
| I-CXL 10min | 0.29±0.92 | 0.09±1.13 | 0.29±2.23 | -0.37±1.1 | 0.097 |
| aP | 0.034 | 0.165 | 0.234 | 0.008 | |
| ΔKflat | |||||
| I-CXL 5min | 0.71±1.19 | 0.53±2.16 | 0.77±2.2 | 1.32±3.32 | 0.146 |
| I-CXL 10min | -0.07±0.99 | -0.23±1.06 | -0.03±0.94 | -0.19±0.9 | 0.287 |
| aP | 0.032 | 0.140 | 0.108 | 0.034 | |
| ΔKmax | |||||
| I-CXL 5min | 2.87±5.17 | 2.22±4.47 | 2.27±5.66 | 1.87±3.29 | 0.012 |
| I-CXL 10min | -0.25±3.69 | -0.94±3.95 | -0.92±3.65 | -0.94±3.00 | 0.033 |
| aP | 0.030 | 0.024 | 0.034 | 0.028 | |
| ΔCCT | |||||
| I-CXL 5min | -7.93±20.14 | -10.4±16.08 | -7±17.49 | -11.13±17.3 | 0.026 |
| I-CXL 10min | -11.65±11.02 | -6.62±12.23 | -9.08±22.96 | -3.92±13.19 | 0.142 |
| aP | 0.447 | 0.400 | 0.764 | 0.141 | |
| ΔECD | |||||
| I-CXL 5min | -15±31 | 12±31 | -18±39 | -11±27 | 0.149 |
| I-CXL 10min | 26±35 | 11±48 | 28±34 | -12±17 | 0.252 |
| aP | 0.237 | 0.624 | 0.538 | 0.169 |
I-CXL: Iontophoresis-assisted corneal cross-linking; UCVA: Uncorrected visual acuity; CDVA: Corrected distance visual acuity; SE: Spherical equivalent; CCT: Corneal thickness at thinnest point; ECD: Endothelial cell density. aComparison between two groups at the same point; bComparison with baseline at 1, 3, 6 and 12mo postoperatively in each group.