Figure 6.
CB7 alleviated the PQ poisoning to lungs in mouse model. (A-D) Typical pro-inflammatory cytokines and ROS-related levels in lungs from mice sacrificed 8 h after ingesting PQ or PQ@CB7 (molar ratio of PQ/CB7 = 1:2, CB7 = 2.71 g/kg) at the PQ dose of 300 mg/kg. Data are presented as means ± SEM, n = 6, and *P < 0.05, **P < 0.01, ***P < 0.001. (E) H&E-stained histopathological sections of lungs from mice sacrificed 8 h after they had ingested saline (control group), PQ or PQ@CB7 (molar ratio of PQ/CB7 = 1:2) at the PQ dose of 300 mg/kg. Scale bar = 100 μm.