Skip to main content
. 2019 Jan 25;9(3):829–836. doi: 10.7150/thno.29902

Figure 4.

Figure 4

Relative autoreactive IgE is associated with higher relative IgE-anti-IL-24 levels. IgE is more lipophilic in sera with higher amounts of autoreactive IgE. (A) The mean relative IgE-anti-IL-24 levels (ratio of IgE-anti-IL-24 to total IgE levels) are two log-scales higher in seven CSU patients than in seven healthy controls. The significance of this difference is P = 0.0006 (Mann Whitney U-test). (B) Percentage of autoreactive IgE (from total IgE) correlates with relative IgE-anti-IL-24 levels (N = 14; Pearson correlation coefficient, r = 0.656; P = 0.0108) in combined data from patients with CSU (black circles, N = 7) and healthy controls (open circles, N = 7). (C) The relative level of IgE-anti-IL-24 was used as a surrogate marker for the whole autoreactive IgE concentration. There is a strong correlation between the ratio of lipophilic IgE to total IgE and the ratio of IgE-anti-IL-24 to total IgE in CSU patients (N = 27; Pearson correlation coefficient, r = 0.754; P < 0.0001).