Figure 1.
Two more aggressive OVCA cell models were established and more aggressive OVCA cells had a higher aerobic glycolysis rate. (A) The OVCA cell models, OVCAR-3high and SK-OV-3high, were triple screened from the OVCAR-3 and SK-OV-3 cell lines, respectively, using Matrigel-coated Transwell chambers. (B-D) Colony formation (B), the migration and invasion (C) and cell growth (D) of the indicated cells were determined. (E-G) The glucose uptake (E), lactate production (F), and PK activity (G) of the indicated cells were detected (n=3).