Figure 2.

Hematoxylin-eosin stained histology sections of the defect edge at 8 weeks postinjury. (A) Low-power view to show structure of the edge of the defect, Bar = 400microns. (B) Higher power view of box region of A to show presence of multicellular chondrocyte clusters and an apparent recruitment of chondrocytes derived from residual cartilage tissue into the new chondrocytes being produced in the fibrous tissue infill. Bar = 400microns. (C) Higher power view of box region of B stained with anti-PCNA antibody with a TRITC-labelled secondary antibody. PCNA activity is shown in red. Bar = 250 µm.