Table 1.
Descriptive statistics of study participants with distribution of sex, migraine subtype, and lifetime depression across groups with an increasing genetic load (reflected by the proportion of affected parents).
| Total group of migraine patients | Subgroups by parents’ migraine status |
Pearson χ2 Test* | |||
|---|---|---|---|---|---|
| No parent affected | One parent affected | Both parents affected | |||
| Age, median (IQR) (years) | 41.9 (32.3–50.0) | 41.7 (31.9–50.0) | 42.2 (33.1–50.2) | 39.5 (29.5–48.2) | |
| Sex | |||||
| Female, n (%) | 2442 (86%) | 885 (36%) | 1418 (58%) | 139 (6%) | χ2(2) = 0.67 |
| Male, n (%) | 387 (14%) | 137 (35%) | 224 (58%) | 26 (7%) | p = 0.72 |
| Migraine subtype | |||||
| MO, n (%) | 1787 (63%) | 674 (38%) | 1019 (57%) | 94 (5%) | χ2(2) = 6.99 |
| MA, n (%) | 1042 (37%) | 348 (33%) | 623 (60%) | 71 (7%) | p = 0.03 |
| Lifetime depression | |||||
| Yes, n (%) | 991 (43%) | 343 (35%) | 581 (59%) | 67 (7%) | χ2(2) = 4.16 |
| No, n (%) | 1292 (57%) | 465 (36%) | 765 (59%) | 62 (5%) | p = 0.13 |
*
Pearson χ2 test comparing distribution of presented variables over the categories of: 0 = no parents affected; 1 = one parent affected; 2 = both parents affected with migraine.
IQR: interquartile range; MO: migraine without aura; MA: migraine with aura.