Table 3.
Particle diameters and span of Man+Leu and mannitol emitted from a large-sized nasal cannula
| DFR (L/min) |
D10 (μm) |
D50 (μm) |
D90 (μm) |
Span |
|---|---|---|---|---|
| Man+Leu | ||||
| 20 | 1.31 ± 0.04 | 3.23 ± 0.24 | 10.6 ± 2.11 | 2.86 ± 0.44 |
| 25 | 1.23 ± 0.03 | 3.28 ± 0.17 | 12.7 ± 2.96 | 3.48 ± 0.83 |
| 30 | 1.26 ± 0.08 | 3.85 ± 0.14 | 14.8 ± 1.48 | 3.51 ± 0.28 |
| Mannitol | ||||
| 20 | 1.95 ± 0.13 | 7.17 ± 1.43 | 62.1 ± 21.3 | 8.67 ± 3.29 |
| 25 | 1.69 ± 0.10 | 4.33 ± 0.33* | 29.5 ± 7.03 | 6.36 ± 1.24 |
| 30 | 1.69 ± 0.08* | 4.45 ± 0.35* | 27.3 ± 5.63* | 5.74 ± 1.04 |
The dose in all experiments was 40 ± 4 mg powder. Each value represents the mean ± SD (n = 3). D10, D50, and D90 are the particle diameters at 10, 50 and 90% of the cumulative particle size, respectively. Significant differences between DFR 20 and 25 L/min or 30 L/min are marked with an asterisk (* p < 0.05)