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. 2019 Feb 14;19:41. doi: 10.1186/s12877-019-1058-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Antihypertensive Adherence Trajectories over 3 Years: Dementia Cases and Non-Dementia Controls Combined (N = 4182). ^a Each individual was assigned to one trajectory group based on the probabilities of individual membership in each trajectory group generated from the model. We used a censored normal model for the 15-day average PDC to accommodate the excess of zeroes and ones at the scale minimum and maximum. Group-based trajectory modeling suggested a 4-group solution for antihypertensive users. The 4 medication adherence trajectories and their 95% confidence intervals are displayed in the Figure. Trajectory groups are labeled based on appearance to aid interpretation. ^b Trajectory group prevalence included near perfect (n = 1877, 37% cases, 46% controls), high (n = 1840, 43% cases, 44% controls), moderate (n = 365, 18% cases, 8% controls) and early poor adherence (n = 100, 1.7% cases, 2.4% controls)