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. 2019 Feb 14;19:41. doi: 10.1186/s12877-019-1058-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Statin Adherence Trajectories over 3 Years: Dementia Cases and Non-Dementia Controls Combined (N = 1279). ^a Each individual was assigned to one trajectory group based on the probabilities of individual membership in each trajectory group generated from the model. We used a censored normal model for the 15-day average PDC to accommodate the excess of zeroes and ones at the scale minimum and maximum. Group-based trajectory modeling suggested a 4-group solution for statin users. The 4 medication adherence trajectories and their 95% confidence intervals are displayed in the Figure. Trajectory groups are labeled based on appearance to aid interpretation. ^b Trajectory group prevalence included high (n = 1004, 75% cases, 79% controls), moderate (n = 192, 20% cases, 14% controls), early poor (n = 43, 2.0% cases, 3.5% controls), and delayed poor adherence (n = 40, 3.4% cases, 3.1% controls)