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. 2019 Feb 15;17:46. doi: 10.1186/s12967-019-1794-6

Table 1.

Characteristics and DED prevalence of the study population

Characteristics Number of subjects (%) Number of patients with DED DED prevalence (%) Chi square P value
Gender 149.0810 < 0.0001
 Male 11,686 (48.85) 6736 57.64
 Female 12,236 (51.15) 7993 65.32
Age (years old) 351.0333 < 0.0001
 < 25 4969 (20.77) 2579 51.90
 25–45 10,895 (45.54) 6648 61.02
 > 45 8058 (33.68) 5502 68.28
Keratorefractive surgery 43.5570 < 0.0001
 No 20,330 (84.98) 12,340 60.70
 Yes 3592 (15.02) 2389 66.51
Diabetes 32.7384 < 0.0001
 No 21,926 (91.66) 13,381 61.03
 Yes 1996 (8.34) 1348 67.54
Arthritis 136.1486 < 0.0001
 No 22,003 (91.98) 13,309 60.49
 Yes 1919 (8.02) 1420 74.00
Thyroid diseases 11.1371 0.0008
 No 22,503 (94.07) 13,796 61.31
 Yes 1419 (5.93) 933 65.75
Antihistamine 65.9711 < 0.0001
 No 22,414 (93.70) 13,652 60.91
 Yes 1508 (6.30) 1077 71.42
OC 6.5310 0.0106
 No 23,122 (96.66) 14,271 61.72
 Yes 800 (3.34) 458 57.25
Diuretics 33.8723 < 0.0001
 No 22,921 (95.82) 14,025 61.19
 Yes 1001 (4.18) 704 70.33
DU drugs 57.8380 < 0.0001
 No 23,361 (97.65) 14,297 61.20
 Yes 561 (2.35) 432 77.01
Diazepam 72.7696 < 0.0001
 No 23,170 (96.86) 14,154 61.09
 Yes 752 (3.14) 575 76.46
CO (days)* 6.3735 0.0116
 < 124 17,338 (72.48) 10,760 62.06
 ≥ 124 6584 (27.52) 3969 60.28
NO2 (days)* 2.9279 0.0871
 < 150 15,968 (66.75) 9771 61.19
 ≥ 150 7954 (33.25) 4958 62.33
O3 (days)* 1349.9078 < 0.0001
 < 125 17,770 (74.28) 9733 54.77
 ≥ 125 6152 (25.72) 4996 81.21
PM10 (days)* 63.8984 < 0.0001
 < 102 15,071 (63.00) 8989 59.64
 ≥ 102 8851 (37.00) 5740 64.85
PM2.5 (days)* 5.0322 0.0249
 < 143 17,195 (71.88) 10,663 62.01
 ≥ 143 6727 (28.12) 4066 60.44
SO2 (days)* 256.7553 < 0.0001
 < 101 17,555 (73.38) 10,276 58.54
 ≥ 101 6367 (26.62) 4453 69.94
Total 23,922 (100.00) 14,729 61.57

* The number of days in which the pollutant concentration exceeds the “extreme value”